E. coli is widely found in nature and threatens the development of broiler production. Therefore, comprehensive prevention and control must be strengthened.

1. Strict sanitation.
Broiler farms should thoroughly clean and disinfect livestock farms, utensils, etc. 30 days prior to entering the chickens. In addition to newly constructed farms, they should
be effectively disinfected more than 4 times in a row. After entering the chicken, the roads and entrances that often move around and in and out should be equipped with a
disinfectant pool or a layer of 5 cm thick quicklime. Strive to avoid cross-breeding chickens and multi-day-old broilers co-exist.

2. Strengthen feeding management.
E. coli in broiler chickens occurs mostly in winter, should do a good job of cold and warm, not only to pay attention to insulation but also take into account the ventilation,
timely removal of harmful gases within the home. Avoid super-density rearing, according to the effective area of ​​the house rearing density is generally 10 to 11 feathers / m2.
Drinking water can be added with 5 × 10 chloride disinfectant or 10 × 10 -6 peracetic acid for disinfection.

3. Early drug control.
According to the author’s experience, Qu Xiao Xiao Oral Liquid (German Bayer products) was successfully treated with Beverage for 2 to 3 days and 20 to 22 days of age in the
brooding period. The results were good, as well as colibacillosis, salmonellosis and Mycoticosis and other diseases have good control and prevention.